Abstract Background The management of unresectable or metastatic gastrointestinal stromal tumors (GISTs) has previously been difficult as they are resistant to conventional chemotherapy and radiation.The development of imatinib mesylate has made a major impact on the management of advanced GISTs.It is apparent that there are sanctuary sites such as
Transition–metal-doped electrocatalysts are considered as low-cost alternatives of Pt and RuO2 electrocatalysts for large scale electrochemical generations of hydrogen and oxygen, respectively.Although, chemical synthesis, typically adopted to produce these electrocatalysts, is scalable but hazardous by-products and chemical wastes create growing
The use of subway tunnel engineering technology has become more professional and refined with the growth of society and the advancement of science and technology.The initial construction process of a subway tunnel shield is the most critical part of the entire engineering system.Shield launching period construction is the most prone to accidents in
The text of the International Ottoman Covenant on Economic, Social and Cultural Rights - a high-class international document on the assurance and legal protection of the human rights - outlined a sum of principles regarding these rights, which fall within the broad range of legal doctrine on fundamental human rights.These principles are not contrar
Abstract Background Obesity is a major public health problem associated with significant medical complications.Main body This review examines 8 primary diseases: type 2 diabetes, hypertension, dementia, non-alcoholic fatty liver disease, polycystic ovarian syndrome, dyslipidemia, cancer, and their manifestations in obese patients.A total of 39 arti